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Related Experiment Videos

Flavonoid glucuronides from Helicteres isora.

K Kamiya1, Y Saiki, T Hama

  • 1Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Japan.

Phytochemistry
|May 31, 2001
PubMed
Summary
This summary is machine-generated.

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Researchers identified five flavonoid glucuronides from Helicteres isora fruit. Three novel compounds were discovered, expanding knowledge of natural product chemistry and potential therapeutic agents.

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry

Background:

  • Helicteres isora is a plant with a history of traditional medicinal use.
  • Flavonoids are a class of plant compounds known for their diverse biological activities.

Purpose of the Study:

  • To isolate and characterize flavonoid glucuronides from Helicteres isora fruit.
  • To identify novel compounds within the plant's phytochemical profile.

Main Methods:

  • Extraction and isolation of compounds from Helicteres isora fruit.
  • Structure elucidation using spectroscopic techniques (e.g., NMR, MS).
  • Hydrolysis experiments to confirm structural features.

Main Results:

  • Five flavonoid glucuronides were successfully isolated.

Related Experiment Videos

  • Three of these compounds were identified as previously unknown: isoscutellarein 4'-methyl ether 8-O-beta-D-glucuronide 6"-n-butyl ester, isoscutellarein 4'-methyl ether 8-O-beta-D-glucuronide 2", 4"-disulfate, and isoscutellarein 8-O-beta-D-glucuronide 2",4"-disulfate.
  • The structures of all isolated compounds were confirmed.

    • Conclusions:

    • The phytochemical investigation of Helicteres isora fruit yielded significant findings.
    • The discovery of novel flavonoid glucuronides contributes to the understanding of plant secondary metabolites.
    • These findings may provide a basis for further research into the pharmacological properties of Helicteres isora.