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Cost-benefit analysis of a Haemophilus influenzae type b meningitis prevention programme in The Philippines

M R Limcangco1, C L Armour, E G Salole

  • 1Department of Pharmacy, College of Pharmacy, University of the Philippines, Manila.

Pharmacoeconomics
|June 1, 2001
PubMed

Insights

Introducing a Haemophilus influenzae type b (Hib) vaccine program in Manila offers significant economic benefits. This vaccination strategy is cost-effective for both the government and society, preventing numerous cases of Hib meningitis.

Area of Science:

  • Public Health
  • Epidemiology
  • Health Economics

Background:

  • Haemophilus influenzae type b (Hib) meningitis causes high mortality and severe sequelae in children under five.
  • Effective vaccines are available to prevent Hib infections.

Purpose of the Study:

  • To evaluate the cost-benefit of a 3-dose Haemophilus influenzae type b (Hib) vaccination schedule in Manila, Philippines.
  • To assess the economic impact from governmental and societal perspectives.

Main Methods:

  • A cost-benefit analysis was conducted using a simulated birth cohort of 100,000 children over a 5-year period.
  • Health outcomes with and without a Hib immunization program were modeled.
  • Data on the extent and cost of Hib sequelae were gathered from medical records in Manila.

Main Results:

  • The model predicted 553 fewer Hib meningitis cases annually per 100,000 children with vaccination.
  • The cost per prevented case was estimated at PHP 56,200.
  • Vaccination yielded substantial savings: PHP 39 million for the government and PHP 255 million for society.

Conclusions:

  • Implementing a Hib vaccination program in Manila presents a positive economic return.
  • The findings support the introduction of a Hib immunization program for significant public health and economic advantages.
Abstract

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