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Updated: Aug 1, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
Bronchial anastomotic stricutre caused by ossification of an intercostal muscle flap
M E Deeb1, D H Sterman, J B Shrager
1Department of Surgery, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
Abstract:
We report a case of heterotopic ossification of a pedicled intercostal muscle flap that had been wrapped circumferentially around a bronchial sleeve anastomosis. This ossification caused severe bronchial stenosis and recurrent pneumonias. Stent insertion failed, and the patient ultimately required completion pneumonectomy. We recommended that caution be used when wrapping intercostal muscle around any important lumen.
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