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The effect of brinase on fibrinogen in vivo
Thrombosis Et Diathesis Haemorrhagica
|April 30, 1975
Abstract:
Brinase infusions in man cause, without excessive lowering of the inhibitor capacity, a slowing of the fibrin polymerization. This is combined with a degradation of the A alpha chain into two major fragments. Both fragments carry crosslinking sites. Brinase infusion also causes positive ethanol gelation. Evidence for the formation of gamma dimers was found.