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Pulmonary embolism in Africans.

O O Elegbeleye, D Femi-pearse

    Tropical and Geographical Medicine
    |March 1, 1975
    PubMed
    Summary

    Pulmonary embolism is a significant risk for African patients, particularly those over 40 with heart disease. This condition has a high mortality rate, suggesting it is not rare in this population.

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    Area of Science:

    • Medicine
    • Cardiology
    • Public Health

    Background:

    • Pulmonary embolism (PE) is a serious condition with high mortality.
    • Understanding the incidence and risk factors for PE in African populations is crucial for public health initiatives.

    Purpose of the Study:

    • To analyze the clinical and autopsy records of pulmonary embolism cases.
    • To determine the incidence, mortality, and associated risk factors of PE at Lagos University Teaching Hospital.

    Main Methods:

    • Retrospective analysis of 54 clinical and autopsy records of PE patients.
    • Data collected from Lagos University Teaching Hospital between 1966 and 1972.

    Main Results:

    • The incidence of PE was 0.1% of all admitted patients, with a 78% mortality rate.
    • Heart disease was the primary associated medical condition.
    • Incidence increased with age after 40, with medical cases being more susceptible than surgical cases.
    • Hemoglobin S possession may predispose individuals to PE.

    Conclusions:

    • Pulmonary embolism is not rare in Africans.
    • Age and pre-existing heart conditions are significant risk factors.
    • Further prospective studies are needed to confirm the role of hemoglobin S in PE predisposition.

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