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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

Filamentous phage associated with recent pandemic strains of Vibrio parahaemolyticus

T Iida1, A Hattori, K Tagomori

  • 1Osaka University, Suita, Osaka, Japan. iida@biken.osaka-u.ac.jp

Emerging Infectious Diseases
|June 1, 2001
PubMed

Insights

Pandemic Vibrio parahaemolyticus strains are linked to a specific filamentous phage. A unique gene within this phage serves as a reliable genetic marker for identifying these concerning bacterial strains.

Area of Science:

  • Microbiology
  • Genetics
  • Epidemiology

Background:

  • Recent emergence of pandemic Vibrio parahaemolyticus strains in Asia and North America.
  • Need for accurate identification methods for these strains.

Purpose of the Study:

  • To identify a specific marker associated with pandemic Vibrio parahaemolyticus strains.
  • To evaluate the utility of this marker for strain identification.

Main Methods:

  • Investigated the association of bacteriophages with pandemic Vibrio parahaemolyticus.
  • Identified a unique open reading frame (ORF) within the associated phage.
  • Validated the phage ORF as a genetic marker.

Main Results:

  • A filamentous phage was found to be specifically associated with pandemic Vibrio parahaemolyticus.
  • A unique open reading frame (ORF) was identified in the phage genome.
  • This ORF proved to be a reliable genetic marker for identifying pandemic strains.

Conclusions:

  • The identified filamentous phage is a key characteristic of pandemic Vibrio parahaemolyticus.
  • The unique phage ORF is a valuable genetic tool for epidemiological surveillance and identification of pandemic strains.

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