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Updated: Aug 7, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
The incidence of glassy corneal striae
Abstract:
Glassy corneal striae (GCS) are fine colorless lines that run parallel to each other in a vertical or near-vertical orientation in the central cornea near the level of Descemet's membrane. It is postulated that GCS "brace" the stroma, thus adding stability to the cornea. The purpose of this study was to determine the incidence of GCS in patients with "normal" corneas and to determine whether a correlation exists between the presence of GCS and gender, age, iris color, or corneal astigmatism (toricity). Modified marginal retro-illumination biomicroscopy was used to evaluate the cornea for the presence of GCS. One hundred thirteen "normal" right corneas were evaluated for the presence of GCS. A total of 85.8% (97/113) of subjects in our study sample exhibited GCS. However, we were unable to establish a statistically significant correlation between the presence of GCS and gender, age, iris color, or corneal toricity.

