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Grover's disease associated with Sarcoptes scabiei
S Kaddu1, R R Müllegger, H Kerl
1Department of Dermatology, Karl Franzens University, Graz, Austria. steve.kaddu@kfunigraz.ac.at
Dermatology (Basel, Switzerland)
|June 1, 2001
Summary
This study reports a rare case where Grover's disease symptoms were caused by Sarcoptes scabiei mites. Prompt treatment for scabies led to a complete cure, highlighting the need to rule out mite infestation in suspected Grover's disease.
Area of Science:
- Dermatology
- Parasitology
Background:
- Grover's disease, also known as transient acantholytic dermatosis, is a papular and pruritic eruption.
- Its exact etiology remains unclear, but it typically presents with specific histopathological findings.
Observation:
- An 83-year-old male presented with itchy papules clinically resembling Grover's disease.
- Histopathology showed suprabasal acantholysis and a lymphocytic infiltrate, consistent with Grover's disease.
- Skin scrapings revealed Sarcoptes scabiei mites, indicating scabies.
Findings:
- The patient experienced a complete resolution of symptoms after treatment with an antiscabies cream.
- This case, along with a literature review, suggests an unusual association between Grover's disease presentation and S. scabiei infestation.
- The histopathological features of Grover's disease can be mimicked by severe scabies.
Implications:
- It is crucial to consider and exclude scabies infestation in patients presenting with clinical and histopathological features of Grover's disease.
- Early diagnosis and treatment of scabies can lead to rapid symptom resolution.
- This finding underscores the importance of thorough dermatological examination to identify treatable causes of pruritic eruptions.