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Node-positive mucosal gastric cancer: a follow-up study
1Gastric Surgery Division, National Cancer Center Hospital, Tokyo, Japan.
Japanese Journal of Clinical Oncology
|June 2, 2001
Summary
Node-positive mucosal gastric cancer is rare but has an excellent prognosis. Gastrectomy with lymphadenectomy offers high survival rates, even with lymph node metastasis.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Lymph node metastasis in mucosal gastric carcinoma is uncommon.
- Prognosis data for these patients is limited.
Purpose of the Study:
- To investigate the clinicopathological features and prognosis of patients with node-positive mucosal gastric cancer.
Main Methods:
- Retrospective study of 45 patients with node-positive mucosal gastric cancer.
- Analysis of gastrectomy and lymphadenectomy procedures.
- Clinicopathological data and clinical status were assessed.
Main Results:
- 87% of patients underwent D2 lymphadenectomy.
- Metastasis was primarily to perigastric nodes (pN1) in 67% of cases.
- Disease-specific 5- and 10-year survival rates were 95% and 89%, respectively, with a median follow-up of 11 years.
Conclusions:
- Nodal metastasis is a significant prognostic factor in gastric cancer.
- Excellent prognosis is achievable for mucosal gastric cancer with lymph node metastasis when treated with gastrectomy and lymphadenectomy.