Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Steroids for otitis media with effusion: a systematic review.

C C Butler1, J H van Der Voort

  • 1Department of Family Medicine, McMaster University, Faculty of Health Sciences, 1200 Main St W, HSC-2V14, Hamilton, Ontario, Canada L8N 3Z5. cbutler@mcmaster.ca

Archives of Pediatrics & Adolescent Medicine
|July 14, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Otitis externa: what is the problem with getting it right? A mixed-methods study in primary and secondary care - ERRATUM.

The Journal of laryngology and otology·2026
Same author

Stop antibiotics when you feel better? Opportunities, challenges and research directions.

JAC-antimicrobial resistance·2024
Same author

Otitis externa: what is the problem with getting it right? A mixed-methods study in primary and secondary care.

The Journal of laryngology and otology·2021
Same author

[Prevalence of microbiologically-confirmed influenza in patients with influenza-like illness in primary care and clinical and epidemiological characteristics].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2021
Same author

Huisarts en wetenschap·2020
Same author

Lower respiratory tract infection in the community: associations between viral aetiology and illness course.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2020
Same journal

Physical Activity Awareness of British Adolescents.

Archives of pediatrics & adolescent medicine·2013
Same journal

About this journal.

Archives of pediatrics & adolescent medicine·2013
Same journal

Picture of the month-diagnosis.

Archives of pediatrics & adolescent medicine·2013
Same journal

Picture of the month-diagnosis.

Archives of pediatrics & adolescent medicine·2013
Same journal

Puget sound, Seattle, washington. March 2006.

Archives of pediatrics & adolescent medicine·2013
Same journal

Talia's shell, July 2008, in Bay Head, New Jersey.

Archives of pediatrics & adolescent medicine·2013
See all related articles

Steroids can quickly resolve otitis media with effusion (OME) in children short-term, but offer no long-term benefits for hearing loss. Therefore, steroid treatment for OME is not recommended.

Area of Science:

  • Pediatrics
  • Otolaryngology
  • Pharmacology

Background:

  • Otitis media with effusion (OME) is a prevalent childhood condition.
  • OME can lead to hearing loss and delayed language development.
  • Current treatment strategies for OME remain a subject of debate.

Purpose of the Study:

  • To evaluate the efficacy of systemic or topical nasal steroids in treating OME.
  • To synthesize evidence from randomized controlled trials on steroid treatment for OME.

Main Methods:

  • Searched major databases (Cochrane, EMBASE, MEDLINE) for relevant randomized controlled trials.
  • Included studies investigating oral or topical nasal steroids, alone or with antibiotics.
  • Extracted data and assessed methodological quality independently.

Related Experiment Videos

Main Results:

  • Oral steroids significantly reduced OME persistence in the short-term (OR 0.22).
  • Oral steroids combined with antibiotics also showed short-term efficacy (OR 0.32).
  • Trends favored steroids in other comparisons, but confidence intervals were not statistically significant for long-term outcomes.

Conclusions:

  • Steroids, alone or with antibiotics, accelerate short-term OME resolution.
  • No evidence supports long-term benefits of steroids for OME-related hearing loss.
  • Current evidence does not support the use of oral or topical nasal steroids for OME treatment.