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Isolated ventricular inversion with situs solitus.

M Quero-Jiménez, I Raposo-Sonnenfeld

    British Heart Journal
    |March 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

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    Isolated ventricular inversion in patients with situs solitus causes cyanotic congenital heart disease and heart failure. Angiocardiography is crucial for diagnosis, and this condition requires similar management to transposition of the great arteries.

    Area of Science:

    • Pediatric Cardiology
    • Congenital Heart Disease
    • Cardiac Anatomy

    Background:

    • Isolated ventricular inversion is a rare congenital heart malformation.
    • This condition, when associated with situs solitus, presents unique clinical challenges.

    Purpose of the Study:

    • To describe the clinical and anatomical findings in patients with isolated ventricular inversion and situs solitus.
    • To review previously reported cases and compare them with new findings.
    • To discuss diagnostic modalities and treatment considerations.

    Main Methods:

    • Review of clinical and anatomical data from two new patients.
    • Compilation and analysis of four previously published cases.
    • Discussion of diagnostic test efficacy, particularly angiocardiography.

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    Main Results:

    • Six patients with isolated ventricular inversion (without pulmonary stenosis) presented with cyanotic congenital heart disease, hypoxemia, and cardiac failure.
    • Increased pulmonary blood flow was a consistent finding.
    • Angiocardiography was identified as the definitive diagnostic tool.

    Conclusions:

    • Isolated ventricular inversion with situs solitus mimics transposition of the great arteries in its pathophysiology, necessitating similar diagnostic and therapeutic approaches.
    • Associated malformations frequently complicate diagnosis and reduce the likelihood of successful surgical outcomes with procedures like the Mustard procedure.