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Associated Chromosome Trap for Identifying Long-range DNA Interactions
Published on: April 23, 2011
Establishing a large DNA data bank using the PowerPlex 1.1 and 2.1 systems
1Forsenic Biology Section, Virginia Division of Forensic Science, 700 North Fifth Street, Richmond, Virginia 23219, USA. Jban@dfs.state.va.usa
Croatian Medical Journal
|June 2, 2001
Summary
Virginia
Area of Science:
- Forensic Science
- Genetics
- Criminology
Background:
- The Virginia Division of Forensic Science recognized the need for a DNA Data Bank in the early 1990s.
- The data bank was intended for comparing convicted sex offender samples against unsolved cases to identify perpetrators.
- Legislation expanded to include all convicted offenders and juveniles tried as adults for felonies.
Purpose of the Study:
- To evaluate the effectiveness of the DNA Data Bank in aiding law enforcement.
- To assess the impact of technological advancements and data bank expansion on crime-solving capabilities.
Main Methods:
- Implementation of a DNA Data Bank for convicted offenders.
- Transition from Restriction Fragment Length Polymorphism (RFLP) to Short Tandem Repeat (STR) DNA analysis technology.
- Analysis of offender samples and forensic case samples for database matching.
Main Results:
- The DNA Data Bank has significantly aided law enforcement in solving crimes.
- An increase in offender sample analyses and unidentified suspect case analyses led to more DNA Data Bank hits.
- By December 31, 2000, the hit rate improved to one hit per 700 samples, a substantial increase from one hit per 2,900 samples in 1997.
Conclusions:
- The DNA Data Bank, particularly with the adoption of STR technology, has proven to be a valuable tool in criminal investigations.
- The expansion of the data bank and increased sample analysis have demonstrably improved its efficacy in identifying perpetrators.
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