Urea in the treatment of epibulbar malignancies

Eight patients with epibulbar malignancies of the eyes were sucessfully treated with urea. One of them presented a malignant melanoma, one a tumour of Kaposi's disease, and six had squamous cell carcinomas. At least four out of these eight patients would have required enucleation of the globe or exenteration of the orbit as an alternative to urea therapy.