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Asymmetric intramolecular C_H insertions of aryldiazoacetates
H M Davies1, M V Grazini, E Aouad
1Department of Chemistry, University at Buffalo, The State University of New York, Bufalo, New York 14260-3000, USA. hdavies@acsu.buffalo.edu
Organic Letters
|June 5, 2001
Abstract:
[reaction: see text] The enantioselectivity of Rh(2)(S-DOSP)(4) catalyzed C-H insertion of aryldiazoacetates is very dependent on the site of the C-H insertion. The highest enantioselectivity is obtained for insertion into methine C-H bonds.