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Antibiotic susceptibility of bacterial strains isolated from urinary tract infections in Poland

K Hryniewicz1, K Szczypa, A Sulikowska

  • 1Department of Internal Medicine, Warsaw University Medical School, Lindleya 1,Warsaw, Poland.

The Journal of Antimicrobial Chemotherapy
|June 5, 2001
PubMed

Insights

Urinary tract infection pathogens in Poland show increasing antimicrobial resistance, particularly Escherichia coli strains producing extended-spectrum beta-lactamases (ESBLs). This highlights the need for updated treatment guidelines to combat drug-resistant bacteria.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pharmacology

Background:

  • Growing global antimicrobial resistance in urinary tract pathogens poses a significant clinical challenge.
  • Conventional antimicrobial agents are becoming less effective against common urinary tract infection (UTI) causing bacteria.

Purpose of the Study:

  • To assess the antimicrobial susceptibility patterns of UTI pathogens in Poland.
  • To identify prevalent etiological agents and their resistance profiles to current antimicrobial drugs.

Main Methods:

  • A multicentre study conducted from July 1998 to May 1999.
  • Involved analysis of 141 hospital-acquired and 460 community-acquired infection pathogens.
  • Identified causative agents including Escherichia coli, Proteus spp., Enterobacteriaceae, Enterococcus spp., and Pseudomonas aeruginosa.

Main Results:

  • Escherichia coli was the most common pathogen (73.0%), showing high susceptibility except for extended-spectrum beta-lactamase (ESBL) producing strains.
  • 38 strains (6.9%) of Enterobacteriaceae tested produced ESBLs.
  • Pseudomonas aeruginosa (10.7%) and Gram-positive cocci like Enterococcus spp. (8.5%) were more frequent in hospital-acquired infections.

Conclusions:

  • Escherichia coli remains a primary UTI pathogen in Poland, but ESBL production is a growing concern.
  • Antimicrobial susceptibility patterns necessitate careful consideration for effective UTI treatment.
  • Monitoring resistance trends is crucial for public health and clinical practice.

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