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Updated: Jun 27, 2026

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on (TRO) Approach
12:12

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on (TRO) Approach

Published on: March 12, 2017

Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination

O Calvo1, J L Manley

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Molecular Cell
|June 8, 2001
PubMed
Summary

Researchers discovered that the transcriptional coactivator PC4 interacts with polyadenylation factor CstF-64. This interaction, conserved in yeast, suggests a role in regulating gene expression and mRNA processing.

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