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Two Subgroups of Gonadotropin Releasing Hormone Neurons Control Gonadotropin Secretion in Rats
Fukuko Kimura1, Toshiya Funabashi
1Dept. of Physiology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan.
Abstract:
Two distinct subgroups of gonadotropin-releasing hormone (GnRH) neurons are involved in the control of luteinizing hormone secretion, at least in rats: one subgroup located in the mediobasal hypothalamus constitutes the GnRH pulse generator associated with opioid neurons, and the other located in the preoptic area constitutes the GnRH surge generator associated with gamma-aminobutyric acid neurons.