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Regulation of Mammalian Gene Expression by Glucose
Guy A. Rutter1, Jeremy M. Tavaré, D. Gail Palmer
1Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK.
Abstract:
Recent data suggest that cells from species as diverse as yeast and mammals may use similar mechanisms to detect changes in nutrient concentration. Here we review recent advances in understanding how glucose regulates gene transcription in mammals.