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Role of Nitric Oxide in Buffering Short-Term Blood Pressure Fluctuations
Harald M. Stauss1, Pontus B. Persson
1Department at Johannes-Müller-Institut für Physiologie, Humboldt-Universität, (Charite), Tucholskystrasse 2, 10117 Berlin, Germany.
Abstract:
Blood pressure instability may promote cardiovascular morbidity. Recent data suggest a role of nitric oxide in stabilizing arterial blood pressure. A rise in blood pressure enhances endothelial shear stress and nitric oxide release. The resulting vasodilation antagonizes the initial increase in blood pressure. This system can respond within 2-10 seconds.