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Blood-testis barrier after transplantation of pituitary cell into dystopic testicle
1Research and Clinical Center of Andrology and Endocrine Organ Transplantation, Department of Operative Surgery and Surgical Anatomy, Russian University of Peoples' Friendship, Moscow, Russia. yevgenyden@mail.ru
Abstract:
A total of 87 allotransplantations of the pituitary were carried out: into intact testicle with or without subsequent transposition into the abdominal cavity and on a previously created model of unilateral cryptorchidism. Histological study showed that pituitary cells retained viability for up to 3 months in all three series. The main structures of the blood-testis barrier (membranes of testicular tubules, tunica albuginea testis, vascular walls, and interstitial tissue) were not damaged, which determined advantages of dystopic testicle in pituitary cell allotransplantation.