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Updated: Aug 15, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
Published on: July 21, 2013
[Current status and controversies on the management of cerebral main trunk occlusion]
1Department of Neurosurgery, Kyorin University School of Medicine.
Insights
Management of cerebral main trunk occlusive disease has advanced with interventional neuroradiology. However, acute embolic stroke and chronic carotid artery occlusion treatments remain unsettled, requiring further review.
Area of Science:
- Neurology
- Interventional Neuroradiology
- Vascular Neurology
Context:
- Cerebral main trunk occlusive disease management has evolved significantly over the past decade.
- Diagnostic and interventional neuroradiology have driven progress in stroke care.
- Established treatment guidelines exist for most stroke types.
Purpose:
- To review the current status and controversies in managing cerebral main trunk occlusive disease.
- To outline previous discussions and ongoing debates in the field.
- To address unsettled aspects of acute embolic ischemia and chronic carotid artery occlusion.
Summary:
- Significant advancements in diagnostic and interventional neuroradiology have improved cerebral main trunk occlusive disease management.
- While guidelines exist for many stroke types, acute embolic ischemia and chronic carotid artery occlusion remain challenging areas.
- This review synthesizes current knowledge and highlights areas of controversy in treatment strategies.
Impact:
- Provides a comprehensive overview of current therapeutic approaches for cerebral main trunk occlusive disease.
- Identifies critical areas requiring further research and clinical trials.
- Aims to guide clinicians in managing complex cerebrovascular conditions.
Abstract:
Management of the cerebral main trunk occlusive disease has proceeded during last decade owing to remarkable progress of diagnostic and interventional neuroradiology. Several large clinical trials have established treatment guidelines in most of stroke management. Concerning cerebral main trunk occlusion, management of acute embolic ischemia and surgical indication for chronic carotid artery occlusion has still remained unsettled. In this article, outline of previous discussion and current status and controversies are reviewed.
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