Related Experiment Video

Updated: Oct 7, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

Coronary artery bypass grafting in patients with dialysis-dependent renal failure: ten-year results

S Gelsomino1, P Da Col, R Frassani

  • 1Department of Cardiovascular Sciences, General Hospital S. Maria della Misericordia, Udine, Italy. sandrogelsomino@virgilio.it

Italian Heart Journal : Official Journal of the Italian Federation of Cardiology
|June 8, 2001
PubMed

Insights

Coronary artery bypass grafting (CABG) in dialysis patients shows acceptable outcomes. Careful patient selection and perioperative management are key for successful outcomes in this high-risk group.

Area of Science:

  • Cardiology
  • Nephrology
  • Surgical Research

Background:

  • Accelerated coronary artery disease is common in chronic renal failure patients on dialysis.
  • Coronary artery bypass grafting (CABG) in dialysis patients remains a debated procedure.

Purpose of the Study:

  • To evaluate the outcomes of CABG in patients with end-stage renal disease on maintenance dialysis.
  • To identify factors influencing mortality and morbidity in this patient population.

Main Methods:

  • Retrospective review of 19 end-stage renal disease patients who underwent CABG between 1990 and 2000.
  • Analysis of operative procedures (CABG alone vs. CABG with valve procedures) and patient demographics.
  • Statistical analysis to determine factors related to mortality.

Main Results:

  • Early (30-day) mortality was 10.5%; non-fatal complications occurred in 31.5% of patients.
  • Actuarial survival rates at 10 years were 54%.
  • Factors significantly related to mortality included advanced age, severe Canadian Cardiovascular Society class, urgent operation, low left ventricular ejection fraction, prior myocardial infarction, high creatinine levels, and long dialysis duration.

Conclusions:

  • CABG in dialysis-dependent chronic renal failure patients yields acceptable results.
  • Accurate patient selection, timely surgical referral, and optimal perioperative care are crucial for improving outcomes.
Abstract

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...