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Related Experiment Videos

Bupropion-induced erythema multiforme.

T W Lineberry1, G E Peters, J M Bostwick

  • 1Department of Psychiatry, Ramstein Air Base, Germany.

Mayo Clinic Proceedings
|June 8, 2001
PubMed
Summary
This summary is machine-generated.

Bupropion, used for depression and smoking cessation, may cause skin reactions like erythema multiforme. Early detection and discontinuation are crucial to prevent severe dermatologic conditions.

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Bupropion is widely prescribed for depression and smoking cessation.
  • Dermatologic adverse effects are a known concern with bupropion use.

Observation:

  • A case of erythema multiforme is reported in a 31-year-old woman after taking sustained-release bupropion (Wellbutrin SR).

Findings:

  • This is the first reported case of erythema multiforme linked to sustained-release bupropion.
  • The patient developed a significant skin reaction.

Implications:

  • Prescribers should monitor patients for rashes and urticaria.
  • Discontinuation of bupropion is recommended upon suspicion of erythema multiforme to avoid severe dermatologic outcomes.