Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pouch and pouchitis.

L Stocchi1, J H Pemberton

  • 1Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Gastroenterology Clinics of North America
|June 8, 2001
PubMed
Summary
This summary is machine-generated.

Pouchitis, an ileal pouch inflammation after IPAA, often responds to antibiotics. Refractory cases may require anti-inflammatory drugs, steroids, or rarely, pouch excision.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative anastomotic configurations and disease recurrence rates of robotic vs. laparoscopic primary ileocolonic resection for Crohn's disease.

Surgical endoscopy·2025
Same author

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting.

Cancers·2025
Same author

Small bowel adenocarcinoma in Crohn's disease: a rare but devastating complication.

Techniques in coloproctology·2020
Same author

Case-matched Comparison of Postoperative Outcomes Following Surgery for Inflammatory Bowel Disease After Exposure to Vedolizumab vs Other Biologics.

Journal of Crohn's & colitis·2019
Same author

Difference in the frequency of pouchitis between ulcerative colitis and familial adenomatous polyposis: is the explanation in peripouch fat?

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2019
Same author

The relationship between mesorectal grading and oncological outcome in rectal adenocarcinoma.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2018
Same journal

Living Donor Intestinal and Liver Transplantation.

Gastroenterology clinics of North America·2026
Same journal

Living Abdominal Organ Donation: A Plan B That Saves Lives.

Gastroenterology clinics of North America·2026
Same journal

Long-Term Outcomes of Living Liver Donors.

Gastroenterology clinics of North America·2026
Same journal

Perioperative Management of Living Liver Donor Patients.

Gastroenterology clinics of North America·2026
Same journal

Living Donor Liver Transplantation for Colorectal Cancer Liver Metastasis.

Gastroenterology clinics of North America·2026
Same journal

Living Donor Liver Graft in Adult Populations: Donor Selection and Workup.

Gastroenterology clinics of North America·2026
See all related articles

Area of Science:

  • Gastroenterology
  • Inflammatory Bowel Disease

Background:

  • Pouchitis is inflammation of the ileal pouch following ileal pouch-anal anastomosis (IPAA).
  • Its etiology remains largely unknown, though often considered a recurrence of ulcerative colitis in the pouch.
  • It rarely affects patients with familial adenomatous polyposis (FAP).

Purpose of the Study:

  • To outline the management strategies for pouchitis.
  • To discuss treatment options for antibiotic-refractory or non-responsive cases.

Main Methods:

  • Review of current medical literature and clinical practice guidelines for pouchitis management.
  • Discussion of therapeutic approaches including antibiotics, anti-inflammatory agents, steroids, and experimental treatments.

Main Results:

Related Experiment Videos

  • Initial treatment typically involves a short course of antibiotics.
  • For persistent or non-responsive pouchitis, anti-inflammatory agents or steroids may be employed.
  • Alternative and experimental therapies show mixed success.

Conclusions:

  • Pouchitis management involves a stepwise approach, starting with antibiotics.
  • Medical management failure may necessitate consideration of alternative drugs or, in rare refractory cases, pouch excision.