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Updated: Oct 7, 2026

Determination of High-affinity Antibody-antigen Binding Kinetics Using Four Biosensor Platforms
Published on: April 17, 2017
Error-compensated kinetic determinations by detecting the reagent in successive reactions
Abstract:
An error-compensated algorithm based on detecting the reagent in successive reactions is proposed. The algorithm was first studied by using simulated data and it was found that it performed well in compensating for the system error and eliminating random noise. Then the algorithm was examined by applying it to the determination of epinephrine and norepinephrine under different experimental conditions. The results revealed that the algorithm compensated errors produced not only by the changes of rate constants, but also by the variation of equilibrium signals.
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