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Related Experiment Videos

Predictable multiple site root coverage using an acellular dermal matrix allograft.

R D Henderson1, H Greenwell, C Drisko

  • 1School of Dentistry, University of Louisville, KY 40292, USA.

Journal of Periodontology
|June 8, 2001
PubMed
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Acellular dermal matrix (ADM) allografts effectively achieve root coverage, with no significant difference based on material orientation. This predictable procedure also increased keratinized tissue in patients undergoing treatment for gingival recession.

Area of Science:

  • Periodontology
  • Regenerative Dentistry
  • Biomaterials

Background:

  • Gingival recession defects are a common clinical concern.
  • Acellular dermal matrix (ADM) allografts are utilized for root coverage procedures.
  • The optimal orientation of ADM for root coverage remains under investigation.

Purpose of the Study:

  • To assess the impact of ADM orientation on root coverage outcomes.
  • To compare ADM root coverage with existing literature.
  • To evaluate ADM's effect on keratinized tissue and creeping attachment.

Main Methods:

  • A randomized, controlled, blinded clinical trial involving 10 patients.
  • Treatment of Miller Class I or II recession defects (> or =3 mm) with a coronally positioned flap and ADM.

Related Experiment Videos

  • ADM placement with either the basement membrane (AB) or connective tissue (AC) side facing the root.

    • Main Results:

    • Both AB and AC orientations achieved approximately 95% mean root coverage.
    • Sixty-eight additional sites also showed ~93% root coverage.
    • A mean increase of 0.80 mm in keratinized tissue was observed; no significant creeping attachment occurred post-2 months.

    Conclusions:

    • ADM allografts provide effective and predictable root coverage.
    • The orientation of the ADM allograft does not influence root coverage or other clinical outcomes.
    • ADM is a viable option for treating gingival recession defects.