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Biflavonoids from Ouratea multiflora.

J D'arc Felicio1, M H Rossi, H R Park

  • 1Laboratório de Química e Farmacologia de Produtos Naturais, Centro de Sanidade Animal, Instituto Biológico, Av. Cons. Rodrigues Alves, 1252, 04014-002, SP, São Paulo, Brazil. felicio@biologico.br

Fitoterapia
|June 8, 2001
PubMed
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Researchers isolated a novel flavone dimer and amenthoflavone from Ouratea multiflora leaves. Their structures were confirmed using advanced spectroscopic techniques, including 2D NMR.

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry

Background:

  • Ouratea multiflora is a plant species known for its potential bioactive compounds.
  • Flavonoids and their dimers are a significant class of natural products with diverse biological activities.

Purpose of the Study:

  • To isolate and characterize novel compounds from the leaves of Ouratea multiflora.
  • To elucidate the chemical structure of isolated natural products using spectroscopic methods.

Main Methods:

  • Phytochemical investigation of Ouratea multiflora leaf extract.
  • Isolation of compounds using chromatographic techniques.
  • Structure elucidation employing spectroscopic methods, including Nuclear Magnetic Resonance (NMR) spectroscopy (1D and 2D NMR).

Main Results:

Related Experiment Videos

  • A new flavone dimer, identified as 3-hydroxy-4",5,7-trimethoxyflavone-(6-->8")-3"-hydroxy-3",4",5",7"-tetramethoxyflavone, was isolated.
  • Amenthoflavone was also isolated from the same plant source.
  • The structures of both compounds were definitively established through comprehensive spectroscopic analysis.

Conclusions:

  • The leaves of Ouratea multiflora are a source of complex flavone derivatives.
  • The identification of this new flavone dimer expands the known phytochemical profile of the Ouratea genus.
  • Spectroscopic methods, particularly 2D NMR, are crucial for the structural determination of complex natural products.