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Renal function and renal disease in the elderly: Part II
1Department of Internal Medicine, University Hospital Maastricht, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands
European Journal of Internal Medicine
|June 8, 2001
Summary
Life expectancy is increasing, leading to more elderly patients with end-stage renal disease (ESRD). Aging kidneys and chronic conditions like type 2 diabetes contribute to this growing challenge in renal replacement therapy.
Area of Science:
- Nephrology
- Geriatrics
- Public Health
Background:
- Global life expectancy has significantly increased over the last century.
- This demographic shift has led to a rise in elderly patients with end-stage renal disease (ESRD).
- The prevalence of chronic diseases associated with aging, such as type 2 diabetes and vascular disease, is increasing.
Purpose of the Study:
- To review the changing patterns of ESRD in the elderly population.
- To explore the multifactorial causes of increased ESRD incidence in older adults.
- To discuss the specific challenges and considerations for renal replacement therapy in elderly patients.
Main Methods:
- Review of epidemiological trends in ESRD.
- Analysis of age-related changes in renal function.
- Examination of the impact of chronic diseases on kidney health in older individuals.
Main Results:
- ESRD patterns have shifted, with a predominance of elderly patients.
- Aging is associated with structural and functional renal deterioration.
- Type 2 diabetes mellitus is a major contributor to morbidity and mortality in older patients due to its vascular complications.
Conclusions:
- The aging population presents unique challenges for managing ESRD.
- Chronic diseases, particularly type 2 diabetes, significantly impact kidney health in the elderly.
- Further discussion on renal replacement therapy for the elderly is warranted (as detailed in Part II).