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Related Experiment Videos

TreeGeneBrowser: phylogenetic data mining of gene sequences from public databases.

I B Jakobsen1, J A Saleeba, M Poidinger

  • 1Australian Genomic Information Centre, University of Sydney, NSW 2006, Australia.

Bioinformatics (Oxford, England)
|June 8, 2001
PubMed
Summary

TreeGeneBrowser facilitates phylogenetic reconstruction by evaluating gene sequence data. It efficiently identifies useful genes and highlights under-represented taxa in sequence databases for evolutionary studies.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Evolutionary Biology

Background:

  • Sequence databases are rich in phylogenetic data but lack tools for comprehensive evaluation.
  • Assessing evolutionary information suitability for phylogenetic reconstruction is challenging.
  • Identifying under-represented taxa for specific gene sequences in databases is difficult.

Purpose of the Study:

  • To develop a tool for inspecting and evaluating gene sequence data for phylogenetic reconstruction.
  • To improve the efficiency of identifying genes suitable for phylogenetic studies.
  • To identify under-represented taxa and taxonomic branches in sequence databases.

Main Methods:

  • Development of TreeGeneBrowser software.
  • Inspection and evaluation of gene sequence data.

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  • Identification of gene suitability and taxonomic representation.

    • Main Results:

    • TreeGeneBrowser enables efficient inspection and evaluation of gene sequence data.
    • The tool aids in identifying genes valuable for specific phylogenetic studies.
    • It effectively pinpoints under-represented taxa and taxonomic branches within sequence databases.

    Conclusions:

    • TreeGeneBrowser enhances the utility of sequence databases for phylogenetic research.
    • The software improves the process of selecting appropriate data for evolutionary analyses.
    • It addresses the need for better assessment of data representation in phylogenetic studies.