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TreeGeneBrowser: phylogenetic data mining of gene sequences from public databases.
I B Jakobsen1, J A Saleeba, M Poidinger
1Australian Genomic Information Centre, University of Sydney, NSW 2006, Australia.
Bioinformatics (Oxford, England)
|June 8, 2001
Summary
TreeGeneBrowser facilitates phylogenetic reconstruction by evaluating gene sequence data. It efficiently identifies useful genes and highlights under-represented taxa in sequence databases for evolutionary studies.
Area of Science:
- Bioinformatics
- Computational Biology
- Evolutionary Biology
Background:
- Sequence databases are rich in phylogenetic data but lack tools for comprehensive evaluation.
- Assessing evolutionary information suitability for phylogenetic reconstruction is challenging.
- Identifying under-represented taxa for specific gene sequences in databases is difficult.
Purpose of the Study:
- To develop a tool for inspecting and evaluating gene sequence data for phylogenetic reconstruction.
- To improve the efficiency of identifying genes suitable for phylogenetic studies.
- To identify under-represented taxa and taxonomic branches in sequence databases.
Main Methods:
- Development of TreeGeneBrowser software.
- Inspection and evaluation of gene sequence data.
- Identification of gene suitability and taxonomic representation.
Main Results:
- TreeGeneBrowser enables efficient inspection and evaluation of gene sequence data.
- The tool aids in identifying genes valuable for specific phylogenetic studies.
- It effectively pinpoints under-represented taxa and taxonomic branches within sequence databases.
Conclusions:
- TreeGeneBrowser enhances the utility of sequence databases for phylogenetic research.
- The software improves the process of selecting appropriate data for evolutionary analyses.
- It addresses the need for better assessment of data representation in phylogenetic studies.