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Related Experiment Videos

The HIB database of annotated UniGene clusters.

B Geier1, G Kastenmüller, M Fellenberg

  • 1MIPS Instituti für Bioinformatik GSF--Forschungszentrum für Umwelt und Gesundheit, GmbH Ingolstädter Landstrasse, 1 85764 Neuherberg, Germany.

Bioinformatics (Oxford, England)
|June 8, 2001
PubMed
Summary

The HumanInfoBase (HIB) is a new database for human gene transcripts. It uses automated analysis and provides a user-friendly interface for exploring gene information.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • Databases of human gene transcripts are crucial for biological research.
  • Existing resources may lack comprehensive automated annotation and user-friendly interfaces.

Purpose of the Study:

  • To introduce the HumanInfoBase (HIB), a novel database for putative human gene transcripts.
  • To describe the automated assembly, analysis, and annotation processes within HIB.

Main Methods:

  • Assembly of UniGene clusters into consensus sequences.
  • Automated sequence analysis and annotation using the PEDANT software system.
  • Classification of predicted transcripts into functional and structural categories.

Main Results:

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  • Development of the HumanInfoBase (HIB) containing annotated human gene transcripts.
  • Implementation of a WWW-based graphical user interface for data visualization.
  • Integration of hyperlinks to external databases for enhanced information retrieval.

Conclusions:

  • The HumanInfoBase (HIB) offers a valuable, automatically annotated resource for human gene transcripts.
  • Its graphical interface facilitates the exploration of transcript assembly and functional sites.
  • HIB enhances accessibility to human gene information through integrated database links.