Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebral abscesses: investigation using apparent diffusion coefficient maps.

A C Guo1, J M Provenzale, L C Cruz

  • 1Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA. acquo@yahoo.com

Neuroradiology
|June 9, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Personalized Computational Causal Modeling of the Alzheimer Disease Biomarker Cascade.

The journal of prevention of Alzheimer's disease·2024
Same author

Expectancy Does Not Predict 18-month Treatment Outcomes with Cognitive Training in Mild Cognitive Impairment.

The journal of prevention of Alzheimer's disease·2024
Same author

Computerized Cognitive Training in Mild Cognitive Impairment: Findings in African Americans and Caucasians.

The journal of prevention of Alzheimer's disease·2024
Same author

Financial Management Skills in Aging, MCI and Dementia: Cross Sectional Relationship to 18F-Florbetapir PET Cortical β-amyloid Deposition.

The journal of prevention of Alzheimer's disease·2019
Same author

Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster.

Chemico-biological interactions·2018
Same author

White Matter Changes Related to Subconcussive Impact Frequency during a Single Season of High School Football.

AJNR. American journal of neuroradiology·2017
Same journal

Correction to: Multiscale characterization and classification of Alzheimer's disease via integration of brain fingerprint radiomics and graph‑theoretical network metrics.

Neuroradiology·2026
Same journal

Reconstruction of complete cerebral arterial anatomy from non-contrast CT using deep learning for pre-thrombectomy guidance.

Neuroradiology·2026
Same journal

The blister sign on non-contrast CT for detection of blood blister-like aneurysms in acute subarachnoid hemorrhage.

Neuroradiology·2026
Same journal

Pre-existing intracranial arterial stenosis independently predicts delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.

Neuroradiology·2026
Same journal

Frontotemporal lobar degeneration in a patient carrying a pathogenic PABPN1 expansion.

Neuroradiology·2026
Same journal

Core-based voxel-wise T2-FLAIR mismatch analysis for differentiation of IDH-mutant astrocytomas from oligodendrogliomas.

Neuroradiology·2026
See all related articles

High signal on diffusion-weighted MRI (DWI) is typical for brain abscesses. However, reduced apparent diffusion coefficients (ADC) indicating restricted diffusion are only consistently seen in larger abscesses, not smaller ones.

Area of Science:

  • Neuroradiology
  • Neuroimaging
  • Diffusion-Weighted MRI

Background:

  • Diffusion-weighted MRI (DWI) with apparent diffusion coefficients (ADC) is used to differentiate brain abscesses from neoplasms.
  • High signal on DWI and low ADC values are considered characteristic findings for abscesses.

Purpose of the Study:

  • To evaluate the consistency of restricted diffusion findings in cerebral abscesses using DWI-derived ADC.
  • To investigate potential factors influencing ADC values in brain abscesses.

Main Methods:

  • Retrospective review of five patients with brain abscesses who underwent DWI MRI.
  • Analysis of ADC values by drawing regions of interest within the abscesses on ADC maps.
  • Comparison of ADC values with normal white matter.

Related Experiment Videos

Main Results:

  • All five abscesses showed high signal on DWI compared to white matter.
  • Three larger abscesses exhibited restricted diffusion (low ADC values).
  • Two smaller abscesses did not show restricted diffusion; their ADC values were similar to white matter.

Conclusions:

  • Restricted diffusion is not a universal finding in all brain abscesses, particularly smaller ones.
  • Absence of restricted diffusion in small abscesses may be due to microenvironmental differences or volume averaging effects.
  • DWI-ADC findings in brain abscesses can vary based on abscess size.