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Extraocular muscle myositis and restrictive strabismus in 10 dogs
I. Allgoewer1, M. Blair, T. Basher
1Free University, Small Animal Clinic, Berlin, Germany; Purdue University, School of Veterinary Medicine, West Lafayette, IN, USA; Veterinary Specialty Hospital, Rancho Santa Fe, CA, USA; North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA; Louisiana State University, School of Veterinary Medicine, Baton Rouge, LA, USA; Free University, Benjamin Franklin Klinikum, Eye Clinic, Berlin, Germany; University of Tennessee, College of Veterinary Medicine, Knoxville, TN, USA; Veterinary Referral Clinic of Mississauga, Mississauga, ON, Canada; University of California San Diego, CA, USA.
Abstract:
Ten cases of uni- or bilateral restrictive ventromedial strabismus in young dogs of different breeds are reported. Clinically, abnormalities were restricted to the extraocular muscles with sparing of the masticatory muscles and limb muscles. This was supported in some cases by imaging studies, electrophysiology, and immunocytochemical assay for antibodies against type 2M fibers. Histologically, there was variable lymphocytic plasmacytic mononuclear cell infiltration and fibrosis. This disorder is similar in many aspects to chronic masticatory myositis with focal myositis and subsequent fibrosis. Surgical correction may restore eye position and vision.