Related Experiment Video

Updated: Sep 12, 2026

Determining the Toxicity of UV Radiation and Chemicals on Primary and Immortalized Human Corneal Epithelial Cells
09:31

Determining the Toxicity of UV Radiation and Chemicals on Primary and Immortalized Human Corneal Epithelial Cells

Published on: July 22, 2021

Cytotoxicity of potential ocular permeation enhancers evaluated on rabbit and human corneal epithelial cell lines

S Burgalassi1, P Chetoni, D Monti

  • 1Department of Bioorganic Chemistry and Biopharmaceutics, University of Pisa, Via Bonanno 33, 1-56126 Pisa, Italy. burgal@farm.unipi.it

Toxicology Letters
|June 9, 2001
PubMed

More Related Videos

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium07:10

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium

Published on: April 6, 2022

Evaluating Therapeutic and Chemical Toxicity Using Organ-Cultured Porcine Corneas and Epithelial Wound Healing03:57

Evaluating Therapeutic and Chemical Toxicity Using Organ-Cultured Porcine Corneas and Epithelial Wound Healing

Published on: January 10, 2025

Related Concept Videos

Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...