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The role of beta-lactamase producing bacteria and bacterial interference in streptococcal tonsillitis
1Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle Street, Washington, DC 20016, USA. brook@mx.afrri.usuhs.mil
International Journal of Antimicrobial Agents
|June 9, 2001
Abstract:
The causes of penicillin failure in eradicating group A beta-haemolytic streptococcal pharyngo-tonsillitis are described. The mechanisms accounting for the failure include the presence in the tonsils of beta-lactamase producing bacteria and the absence of bacterial interference. The use of antimicrobials that can overcome and modulate these two phenomena and achieve better cure of the infection is described.