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Cimetidine-induced dystonic reaction

R S Peiris1, B F Peckler

  • 1Department of Emergency Medicine, St. Barnabus Hospital, Bronx, New York, USA.

A 39-year-old woman presented to the Emergency Department complaining of nausea and vomiting. The patient was given intravenous cimetidine for epigastric pain and subsequently developed a dystonic reaction. Administration of cimetidine, an H2 receptor antagonist, is an uncommon cause of dystonic reaction. We discuss the pathophysiology, diagnosis, and treatment.

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