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Neurosarcoidosis Associated with Hodgkin's Disease; Malignancy
Carol Alliot1, Bernard Desablens, Stephanie Tabuteau
1Department of Blood Diseases, University Hospital of Amiens 80054, Amiens Cedex 1, France.
Abstract:
Sarcoidosis is a granulomatous disease of undetermined origin. The association of sarcoidosis with malignant lymphoma is a rare but possibly nonfortuitous event. The authors report on the case of a 26-year-old male patient presenting with lymphnode sarcoidosis which evolved into neurosarcoidosis. The evolution was responded to corticosteroid therapy. Thirty-three months after the diagnosis of neurosarcoidosis, the patient presented with cervical Hodgkin's disease which was successfully treated by chemotherapy and radiotherapy. The pathophysiological mechanisms and possible associations are briefly discussed.
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