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[Simultaneous occurrence of Basedow's disease and autoimmune hemolytic anemia]
Y Shimohakamada1, N Fukuda, K Shinohara
1Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital.
Abstract:
A 43-year-old man with a 7-year history of low antinuclear factor titer developed Basedow's disease and autoimmune hemolytic anemia (AIHA) simultaneously. Such simultaneous occurrence of these autoimmune disorders has been reported only rarely. Administration of methimazole for Basedow's disease and prednisolone for AIHA was effective for ameliorating both conditions. The patient had the HLA DR2, DRB1 1501 and DPB1 0501 alleles, suggesting a genetic predisposition for these diseases.