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Related Experiment Videos

Coccidioidomycosis presenting as liver abscess.

S Thomas1, S Basu, R Dutta

  • 1Department of Surgery, Lady Hardinge Medical College, Shaheed Bhagat Singh Marg, New Delhi. drshajithomas@yahoo.com

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|June 13, 2001
PubMed
Summary

A liver abscess initially treated for amebiasis was rediagnosed as coccidioidomycosis. Antifungal treatment with amphotericin-B led to complete resolution, demonstrating effective management of this rare fungal infection.

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Hepatology

Background:

  • Liver abscesses are typically treated with aspiration and antibiotics or antiamebic agents.
  • Coccidioidomycosis is a fungal infection endemic to certain regions, rarely presenting as a liver abscess.

Observation:

  • A young adult male presented with persistent right upper quadrant abdominal pain and a large liver abscess despite initial antiamebic therapy.
  • Imaging revealed the abscess was increasing in size, prompting further investigation.

Findings:

  • Repeat aspiration and culture confirmed the liver abscess was caused by Coccidioides species, a fungal pathogen.
  • Treatment with amphotericin-B resulted in complete resolution of the abscess and symptoms.

Implications:

Related Experiment Videos

  • This case highlights the importance of considering fungal infections, such as coccidioidomycosis, in the differential diagnosis of refractory liver abscesses.
  • Early and accurate diagnosis with appropriate antifungal therapy is crucial for successful outcomes in patients with fungal liver abscesses.