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Updated: Aug 14, 2026

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
Management of knee pain and stiffness after total knee arthroplasty
1Orthopedics International, LTD PS, Seattle, Washington 98122, USA. pescranton@msn.com
Abstract:
This article reviews 33 patients who presented with persistent pain, inadequate knee motion, or both after total knee arthroplasty. Of 33 patients, 26 had inadequate motion treated by closed manipulation, arthroscopic manipulation, or a modified open release manipulation. In 23 patients, these procedures were successful. Of the 26 patients, 85% had a history of previous knee surgery or diabetes mellitus. The average gain in range of motion was not different in comparing early (<12 weeks) manipulation versus late (>12 weeks) manipulation. Seven of the 33 patients presenting with pain, swelling, inadequate motion, or snapping sensations had either failure of bonding between the polymethyl methacrylate and the components (4 patients) or painful fibrous intra-articular bands (3 patients). These patients were treated successfully either by recementing the components or by arthroscopic fibrous band release.

