[Analysis of DNA status in bone marrow cells of mice internally irradiated with 90Sr ]
E A Priakhin1, V S Korytnyĭ, A V Akleev
1Ural Research Center for Radiation Medicine, Chelyabinsk, 454076 Russia. pryakhin@urcrm.chel.su
Abstract:
The response of bone marrow cells of CBA mice injected with 22.2, 222 and 592 kBq/animal to additional gamma-irradiation (3 Gy) for testing purposes was evaluated using SCG (Comet assay). A decrease in induction of DNA damage right after additional gamma-irradiation was determined. It correlated with bone marrow cell quantity and the tail length before additional gamma-irradiation. The results support the suggestion about the activation of DNA repair in bone marrow cells under exposure to 90Sr in vivo.
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