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Updated: Aug 15, 2026
FISH for Pre-implantation Genetic Diagnosis
Published on: February 24, 2011
Preimplantation genetic diagnosis in cattle: a review
1Agricultural Research Centre of Finland, MTT, FIN-31600 Jokioinen, Finland. bodo@abc.hu
Abstract:
Preimplantation Genetic Diagnosis (PGD) is reviewed and novel fields where it may be applied are investigated. Technical advances of PGD in cattle embryos have already enabled its integration as a part of the MOET (Multiple Ovulation Embryo Transfer) breeding system. PGD for well-defined selection targets can enhance cattle breeding and embryo trade. It allows embryo selection according to their sex, and it may be used to breed special cow lines, or top bulls, by selecting embryos for valuable production traits using Marker Assisted Selection (MAS). A good allelic profile and/or the insertion of a transgene can be detected by PGD. This review article presents the technical requirements for PGD, and shows that this biotechnological method has great economic potential.
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