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Published on: September 16, 2022
Potential diagnostic test for experimental and natural ovine Taenia hydatigena cysticercosis
M R Panda1, S Ghosh, T K Varma
1Division of Parasitology, Indian Veterinary Research Institute, Izatnagar 243 122, India.
Abstract:
An ion-exchange chromatographic fraction of Taenia hydatigena metacestode was evaluated for use in the immunodiagnosis of ovine cysticercosis. Analysis of the fraction by sodium dodecyl sulphate--polyacrylamide gel electrophoresis revealed the presence of a 68 KDa protein. Antibodies against the isolated protein were detected in 7 out of 10 experimentally infected lambs. The diagnostic potential of the 68 KDa protein was further confirmed by testing sera from naturally infected post-mortem positive (PM+) and from apparently healthy groups of animals. Eighty % and 8% of animals were found positive by enzyme-linked immunosorbent assay (ELISA) in the groups of PM+ and apparently non-infected lambs, respectively.

