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Updated: Oct 7, 2026
P50 Sensory Gating in Infants
Published on: December 26, 2013
Reduced gating of middle-latency auditory evoked potentials (P50) in migraine patients: another indication of
A Ambrosini1, V De Pasqua, J Afra
1Headache Clinics - IRCCS Neuromed via Atinense, 18, I-86077 , Pozzilli (Isernia), Italy.
Abstract:
Habituation of cortical evoked responses to repetitive stimuli is reduced in migraine between attacks. To explore another aspect of information processing, we measured auditory sensory gating. The amplitude of the P50 response to the second of two homologous stimuli was significantly less reduced in migraineurs than in healthy volunteers. This lack of auditory sensory gating may be due to a hypofunction of monoaminergic subcortico-cortical pathways, which is also supposed to cause the interictal deficit of cortical habituation to repetitive stimuli.
