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Updated: Aug 2, 2026

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Measuring Lactase Enzymatic Activity in the Teaching Lab
Published on: August 6, 2018
Long-term acceptance of low-lactose milk
The American Journal of Clinical Nutrition
|October 1, 1979
Summary
Low-lactose milk, made with yeast lactase, significantly reduces digestive symptoms for individuals with lactose intolerance. This nutritious alternative allows for greater milk consumption with fewer adverse effects compared to regular milk.
Area of Science:
- Food Science
- Gastroenterology
- Nutrition
Background:
- Lactose intolerance affects a significant portion of the population, leading to digestive discomfort.
- Traditional dairy consumption can be limited for individuals with lactose intolerance due to adverse symptoms.
Purpose of the Study:
- To evaluate the efficacy and acceptance of low-lactose milk in individuals with and without lactose intolerance.
- To compare symptom profiles between low-lactose milk and unmodified cow's milk.
Main Methods:
- Low-lactose milk was produced using yeast lactase.
- A double-blind study involved 31 volunteers (16 tolerant, 15 intolerant) consuming 500 ml of low-lactose milk twice daily for one month.
- Subjects also consumed unmodified milk on three occasions, with symptom recording during baseline and testing periods.
Main Results:
- Low-lactose milk demonstrated excellent acceptance among all participants.
- No significant symptom differences were observed between tolerant and intolerant groups when consuming low-lactose milk.
- Unmodified milk induced severe symptoms exclusively in lactose-intolerant individuals.
Conclusions:
- Low-lactose milk is a well-accepted alternative for individuals with lactose intolerance.
- This product enables increased intake of nutritious dairy for those with lactose intolerance, minimizing or eliminating symptoms associated with regular milk.
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