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Updated: Aug 15, 2026

Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection
Published on: July 16, 2018
[Non-neoplastic hypertrophic osteoarthropathy due to infected aortic prosthesis. Diagnostic imaging aspects]
W Golder1, M Schnorfeil, J Braun
1Abteilung Radiologie und Nuklearmedizin, Klinikum Benjamin Franklin, Freie Universität Berlin, Hindenburgdamm 30, 12200 Berlin. golder@cipmail.ukbf.fu-berlin.de
Abstract:
Secondary hypertrophic osteoarthropathy of the legs is a rare complication of arterial graft surgery. The syndrome is composed of arthralgias, clubbing of the toes and periostosis of the long bones and is usually associated with an infected aortic prosthesis. Often a CT-guided biopsy is performed in order to identify the graft as the primary focus. In addition to the lamellar periostosis demonstrable by conventional radiographs, a vast edema of the bone marrow and surrounding soft tissue is disclosed by MRI. Imaging promotes the early surgical reintervention.
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