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Compression for venous leg ulcers.

N Cullum1, E A Nelson, A W Fletcher

  • 1Centre for Evidence Based Nursing, Department of Health Studies, University of York, Genesis 6, York Science Park, York, UK, YO10 5DQ. nac2@york.ac.uk

The Cochrane Database of Systematic Reviews
|June 19, 2001
PubMed
Summary
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Compression therapy significantly improves venous leg ulcer healing compared to no compression. Multi-layered systems and high compression are more effective than single-layered or low compression treatments.

Area of Science:

  • Vascular Medicine
  • Wound Healing
  • Medical Devices

Background:

  • Venous leg ulcers represent a significant clinical challenge, impacting patient quality of life and healthcare costs.
  • Compression therapy is a cornerstone in the management of venous leg ulcers, aiming to improve venous return and promote healing.

Purpose of the Study:

  • To systematically evaluate the effectiveness of compression bandaging and stockings in treating venous leg ulcers.
  • To assess the cost-effectiveness of different compression regimens for venous leg ulcers.

Main Methods:

  • A comprehensive literature search was conducted across 19 databases, supplemented by hand searching and contacting manufacturers.
  • Twenty-two randomized controlled trials (RCTs) involving compression bandaging or stockings for venous leg ulcers were included.

Related Experiment Videos

  • Ulcer healing was the primary endpoint, with data extraction and verification performed independently by two reviewers.

    • Main Results:

    • Compression therapy was found to be more effective than no compression in promoting ulcer healing (4/6 trials).
    • Multi-layered compression systems demonstrated superior effectiveness compared to single-layered systems (4 trials).
    • High compression was more effective than low compression, with no significant differences noted between various high-compression multi-layered systems.

    Conclusions:

    • Compression therapy is effective in increasing venous leg ulcer healing rates.
    • Multi-layered and high-compression bandaging systems are superior to single-layered and low-compression alternatives.
    • Further research is needed to establish the cost-effectiveness of different compression strategies.