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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Jul 13, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Post implantation adjustable intraocular lenses.

D M Schwartz1, J M Jethmalani, C A Sandstedt

  • 1Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA. schwartz@sirius.com

Ophthalmology Clinics of North America
|June 19, 2001
PubMed
Summary

New photosensitive intraocular lenses (IOLs) allow for precise laser adjustment after cataract and phakic IOL surgery. This technology corrects refractive errors, offering excellent biocompatibility and significant power adjustability.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Optical Engineering

Background:

  • Persistent refractive errors can occur after traditional cataract and phakic intraocular lens (IOL) surgery.
  • Accurate post-operative refractive correction remains a clinical challenge.

Purpose of the Study:

  • To introduce and evaluate photosensitive silicone IOLs for post-operative refractive error correction.
  • To assess the laser adjustability and biocompatibility of these novel IOLs.

Main Methods:

  • Development of photosensitive silicone IOL formulations.
  • Utilizing laser technology for precise adjustment of IOL power.
  • Evaluating IOL power adjustment for spherical and toric errors post-operatively.

Main Results:

  • Demonstrated precise laser adjustment of IOL power.
  • Achieved correction of spherical and toric refractive errors.
  • Observed excellent biocompatibility and adjustability exceeding five diopters.

Conclusions:

  • Photosensitive silicone IOLs offer a viable solution for eliminating persistent refractive errors.
  • Laser adjustability provides a powerful tool for fine-tuning visual outcomes after IOL implantation.