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Deer Mice As Laboratory Animals.

Charlotte P. Joyner1, Lisa C. Myrick, Janet P. Crossland

  • 1University of South Carolina, Columbia, South Carolina, USA.

ILAR Journal
|June 15, 2001
PubMed
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Deer mice (Peromyscus maniculatus) are abundant North American rodents. They serve as vital disease vectors and valuable research models, easily bred in captivity for scientific study.

Area of Science:

  • Ecology
  • Zoology
  • Veterinary Medicine

Background:

  • Laboratory mice (Mus) and rats (Rattus) are standard research models.
  • Deer mice (Peromyscus maniculatus) and related species are increasingly used as alternative models.
  • Peromyscus rodents are widespread in North America and ecologically significant.

Purpose of the Study:

  • To highlight the ecological importance of Peromyscus rodents.
  • To discuss their role in disease transmission.
  • To present their utility as laboratory research models.

Main Methods:

  • Review of ecological roles and disease vector status.
  • Assessment of captive breeding and husbandry protocols.
  • Information on available research stocks.

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Main Results:

  • Peromyscus species are abundant and inhabit diverse environments.
  • They are key hosts for disease vectors, including Lyme disease bacteria and hantaviruses.
  • Deer mice are suitable for laboratory research and easily bred in captivity.

Conclusions:

  • Deer mice are ecologically important and serve as critical reservoirs for vector-borne diseases.
  • Their adaptability to captivity makes them valuable models for diverse research applications.
  • Well-characterized stocks are available for research and education.