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Biochemical and bacteriological study of urinary calculi
H L Sohshang1, M A Singh, N G Singh
1Regional Institute of Medical Sciences, Imphal-795 004, India.
The Journal of Communicable Diseases
|June 16, 2001
Summary
This study investigated 100 kidney stones, finding that nearly half had bacterial infections. Escherichia coli was the most common bacteria, and calcium oxalate and phosphate were the most frequent stone components.
Area of Science:
- Urology
- Microbiology
- Biochemistry
Background:
- Kidney stones (renal calculi) are a significant health concern.
- Understanding the composition and microbial associations of kidney stones is crucial for effective treatment and prevention.
Purpose of the Study:
- To conduct a biochemical and bacteriological analysis of kidney stones and associated urine samples.
- To identify common bacterial pathogens and chemical constituents in renal calculi.
Main Methods:
- Analysis of urine, nidus, and chemical composition of 100 kidney calculi.
- Bacteriological culture of urine and calculi nidus.
- Chemical analysis to determine stone composition.
Main Results:
- 47% of cases showed positive urine and nidus cultures.
- Escherichia coli was the most frequently isolated bacterium.
- Calcium was the most common radical; uric acid was the rarest.
- Calculi were primarily composed of calcium oxalate/phosphate, followed by struvite and mixed stones.
Conclusions:
- Bacterial infections, particularly with Escherichia coli, are frequently associated with kidney stones.
- Calcium oxalate and phosphate are the predominant chemical components of renal calculi in this region.
- Findings highlight the importance of considering both chemical composition and microbial factors in kidney stone management.